Job Description

Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Scientific Director Medicinal Chemistry What you will do Let’s do this. Let’s change the world. Amgen is hiring in the department of Medicinal Chemistry at our Research and Development facility in South San Francisco CA (ASF) where we are building brand new state-of-the art chemistry labs. This Scientific Director role will assume a scientific leadership position in an expanding medicinal chemistry group of emerging small molecule drug discovery programs at our South San Francisco site. Responsibilities Build and lead a high-performing medicinal chemistry team, augmented by computational chemistry and external contract research organizations (CROs) to deliver clinical candidates Lead as a PTL (Project Team Lead) or PTR (project Team Representative) of small molecule (SM) programs across multiple Therapeutic Areas (TAs) and modalities Lead a group of scientists and develop high performing teams with an inclusive and innovative culture in a modality agnostic manner Partner with biology, pharmacology, and development teams to translate biological insights into actionable clinical strategies Stay abreast of the latest advancements in medicinal chemistry, finding opportunities for external partnerships, collaborations, and integration of new technologies Participate as an engaged member of a highly interactive Medicinal Chemistry department, contributing scientific knowledge and leadership across projects and geographic locations Provide clear, concise and impactful communications to colleagues and senior leadership describing project objectives and results Partners with Legal team to protect Amgen’s estate of innovative small molecules Participate in evaluation of external assets, platforms and technologies What we expect of you We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a Scientific Director with these qualifications. Basic Qualifications: Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] and 5 years of medicinal chemistry experience or Master’s degree and 8 years of medicinal chemistry experience or Bachelor’s degree and 10 years of medicinal chemistry experience Preferred Qualifications: Ph.D. in Organic Chemistry, or a related field Minimum of 14 years of experience in medicinal chemistry within pharmaceutical or biotech industry, with at least 4 years in a project leadership role and as a manager of medicinal chemistry team leads Demonstrated expertise in small molecule drug discovery, structure- and property-based design, and lead optimization High level knowledge of current medicinal chemistry enabling technologies including parallel synthesis, screening techniques, DNA encoded libraries, and ML/generative chemistry Strong record of medicinal chemistry patent applications and peer review publications Consistent track record of advancing compounds from discovery through clinical stages Exceptional leadership and team-building skills, with a collaborative mindset and the ability to mentor and develop scientific talent Excellent communication and presentation skills, with the ability to convey complex scientific concepts to diverse audiences Full-time onsite at our South San Francisco campus What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models, including remote and hybrid work arrangements, where possible Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. #J-18808-Ljbffr Amgen SA

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