Job Description
Role and Responsibilities
- Independently design synthetic strategies and use those strategies to synthesize and characterize precursor compounds, starting materials, intermediates, reference compounds, and new chemical entities
- Design small-molecule drug candidates based on in vitro and in vivo biological activity, ADME/PK, physicochemical and IP-relevant data.
- Purify and characterize molecules with standard analytical techniques (e.g. HPLC, LCMS, NMR)
- Use computation and structural data and information to design molecules
- Perform research and/or development in collaboration with others in chemistry and biology; make detailed observations and analyzes data.
- Prepare batch records, technical reports, summaries, protocols and quantitative analyses
- Write and review manuscripts for publication
- Provide support in corporate research and development of patent applications
- Develop strategies to ensure effective achievement of scientific objectives
- Uses skills to contribute to development of company objectives and principles and to achieve goals in creative and effective ways
- Exercises independent judgment in selecting methods, techniques and evaluation criteria for obtaining results
Qualifications and Education Requirements
- PhD in Chemistry plus 5+ years of related experience in pharmaceutical or biotechnology industry or equivalent.
- Demonstrated expertise in synthetic organic chemistry
- Must possess expert knowledge of scientific principles and concepts.
- A solid understanding of modern analytical techniques (NMR, HPLC, MS)
- Excellent verbal and written communication skills and the ability to collaborate effectively within a multidisciplinary team
Preferred Skills
- Experience in designing and synthesizing PROTACs or molecular glues is strongly preferred
- Molecular modeling and computational methods
- Able to manage outside vendor collaborations
- Flexibility and willingness to solve problems that fall outside of immediate area of expertise
- Work independently in an interdisciplinary, fast-paced, often changing environment.
- Committed to the values of integrity, accountability, transparency, and drive.
Local candidates only.
Salary Range: $160,000 to $195,000
Job Tags
Local area, Immediate start,